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Diet Drug Differences

Here we attempt to explain the differences between the different types of diet pills and weight loss drugs that are available by prescription. There are essentially 3 different kinds of weight loss actions employed by the different diet pills:

  • Sympathomimetic family of appetite suppressants - stimulates the central nervous system (nerves and brain), which increases your heart rate and blood pressure and decreases your appetite.
  • Stomach lipase inhibitor (a fat blocker) - works in your digestive system to block about one-third of the fat in the food you eat from being digested. Enzymes in your digestive system, called lipases, help digest (or break down) fat.
  • Sibutramine - Balances two very important brain chemicals, serotonin and norepinephrine. This helps to increase metabolism and causes a feeling of fullness and increased energy levels. Studies indicate that sibutramine assists in both weight loss and management.

Although these differences are the primary ones, there can also be a difference between the diet pills themselves, which can affect your choice of weight loss drug.

It is important to read the information on this page together with the drug information provided for each of the different diet pills to ensure that you understand all the possible side effects of each drug and that you fully understand the difference between each weight loss drug.

Weight Loss Drug / Diet Pill
Active Ingredient
Brand Trade or Generic
Primary Action
Notable Differences
(Difference between the diet pills)
Phentermine Phentermine Hydrochloride (HCL) Generic Sympathomimetic family of appetite suppressants Cheapest and most popular of the prescription diet pills
Adipex Phentermine Hydrochloride (HCL) Brand of Phentermine Sympathomimetic family of appetite suppressants The most popular brand name Phentermine. Maximum strength 30mg Phentermine base
Bontril Phendimetrazine tartrate Trade Name Sympathomimetic family of appetite suppressants Has the least side effects of any of the appetite suppressant medications. Slow Release formula provides added benefit. Slow release are 105mg as opposed to 35mg
Phendimetrazine Phendimetrazine tartrate Generic Sympathomimetic family of appetite suppressants Cheaper, generic version of bontril. Has the least side effects of any of the appetite suppressant medications. Slow Release formula provides added benefit. Slow release are 105mg as opposed to 35mg
Didrex Benzphetamine Trade Name Sympathomimetic family of appetite suppressants Considered to be the strongest of these type of weight loss drugs
Ionamin Phentermine Hydrochloride (HCL) Brand of Phentermine Sympathomimetic family of appetite suppressants Set in resin, to produce a time release medication / pill. Some people, with sensitive stomachs or other reactions to immediate release Phentermine or Adipex, prefer Ionamin.
Meridia Sibutramine Trade Name Affects appetite control centers in the brain. Reduces food intake by increasing satiety. Not an appetite suppressant Balances two very important brain chemicals, serotonin and norepinephrine. This helps to increase metabolism and causes a feeling of fullness and increased energy levels. Studies indicate that sibutramine assists in both weight loss and management.
Tenuate (Dospan) Diethylpropion hydrochloride Trade Name Sympathomimetic family of appetite suppressants In Diethylpropion hydrochloride tablets, diethylpropion hydrochloride is dispersed in a hydrophilic matrix. On exposure to water, the diethylpropion hydrochloride is released at a relatively uniform rate as a result of slow hydration of the matrix. The result is controlled release of the anorectic agent. DIETHYLPROPION (Tenuate Dospan®) is a medicine used to decrease appetite in over weight patients. Generic diethylpropion hydrochloride sustained-release tablets are available.
Xenical Orlistat Trade Name Stomach lipase inhibitor (a fat blocker) Unlike other commonly prescribed weight-loss medications, Xenical is not an appetite suppressant and does not have a direct effect on the brain. Instead, it works in your digestive system to block about one-third of the fat in the food you eat from being digested. Enzymes in your digestive system, called lipases, help digest (or break down) fat. When taken with meals, Xenical attaches to the lipases and blocks them from breaking down some of the fat you have eaten. The undigested fat cannot be absorbed and is eliminated in your bowel movements.

Diet pills - the difference between the different types

We hope that the above information explains the difference between Phentermine and Ionamin and Adipex. That it clarifies the difference between phentermine, tenuate didrex and bontril and that it helps you to understand the difference between xenical meridia and phentermine. We have attempted to compare the different prescription diet pills by their ingredients and primary actions to help you better understand the difference between them and to help you decide which of the diet pills is right for your weight loss needs.

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